Kinetics of Serologic Responses to MERS Coronavirus Infection in Humans, South Korea
Identifieur interne : 001731 ( Main/Exploration ); précédent : 001730; suivant : 001732Kinetics of Serologic Responses to MERS Coronavirus Infection in Humans, South Korea
Auteurs : Wan Beom Park ; Ranawaka A. P. M. Perera ; Pyoeng Gyun Choe ; Eric H. Y. Lau ; Seong Jin Choi ; June Young Chun ; Hong Sang Oh ; Kyoung-Ho Song ; Ji Hwan Bang ; Eu Suk Kim ; Hong Bin Kim ; Sang Won Park ; Nam Joong Kim ; Leo Lit Man Poon ; Malik Peiris ; Myoung-Don OhSource :
- Emerging Infectious Diseases [ 1080-6040 ] ; 2015.
Descripteurs français
- KwdFr :
- Affinité des anticorps, Animaux, Anticorps antiviraux (immunologie), Chameaux (immunologie), Cinétique, Coronavirus du syndrome respiratoire du Moyen-Orient (immunologie), Coronavirus du syndrome respiratoire du Moyen-Orient (pathogénicité), Femelle, Humains (sang), Humains (virologie), Infections à coronavirus (anatomopathologie), Infections à coronavirus (immunologie), Infections à coronavirus (épidémiologie), Mâle, Production d'anticorps (immunologie), République de Corée (épidémiologie).
- MESH :
- anatomopathologie : Infections à coronavirus.
- immunologie : Anticorps antiviraux, Chameaux, Coronavirus du syndrome respiratoire du Moyen-Orient, Infections à coronavirus, Production d'anticorps.
- pathogénicité : Coronavirus du syndrome respiratoire du Moyen-Orient.
- sang : Humains.
- virologie : Humains.
- épidémiologie : Infections à coronavirus, République de Corée.
- Affinité des anticorps, Animaux, Cinétique, Femelle, Mâle.
English descriptors
- KwdEn :
- Animals, Antibodies, Viral (immunology), Antibody Affinity, Antibody Formation (immunology), Camelus (immunology), Coronavirus Infections (epidemiology), Coronavirus Infections (immunology), Coronavirus Infections (pathology), Female, Humans (blood), Humans (virology), Kinetics, Male, Middle East Respiratory Syndrome Coronavirus (immunology), Middle East Respiratory Syndrome Coronavirus (pathogenicity), Republic of Korea (epidemiology).
- MESH :
- chemical , immunology : Antibodies, Viral.
- blood : Humans.
- epidemiology : Coronavirus Infections, Republic of Korea.
- immunology : Antibody Formation, Camelus, Coronavirus Infections, Middle East Respiratory Syndrome Coronavirus.
- pathogenicity : Middle East Respiratory Syndrome Coronavirus.
- pathology : Coronavirus Infections.
- virology : Humans.
- Animals, Antibody Affinity, Female, Kinetics, Male.
Abstract
We investigated the kinetics of serologic responses to Middle East respiratory syndrome coronavirus (MERS-CoV) infection by using virus neutralization and MERS-CoV S1 IgG ELISA tests. In most patients, robust antibody responses developed by the third week of illness. Delayed antibody responses with the neutralization test were associated with more severe disease.
Url:
DOI: 10.3201/eid2112.151421
PubMed: 26583829
PubMed Central: 4672454
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>We investigated the kinetics of serologic responses to Middle East respiratory syndrome coronavirus (MERS-CoV) infection by using virus neutralization and MERS-CoV S1 IgG ELISA tests. In most patients, robust antibody responses developed by the third week of illness. Delayed antibody responses with the neutralization test were associated with more severe disease.</p>
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<name sortKey="Choe, Pyoeng Gyun" sort="Choe, Pyoeng Gyun" uniqKey="Choe P" first="Pyoeng Gyun" last="Choe">Pyoeng Gyun Choe</name>
<name sortKey="Choi, Seong Jin" sort="Choi, Seong Jin" uniqKey="Choi S" first="Seong Jin" last="Choi">Seong Jin Choi</name>
<name sortKey="Chun, June Young" sort="Chun, June Young" uniqKey="Chun J" first="June Young" last="Chun">June Young Chun</name>
<name sortKey="Kim, Eu Suk" sort="Kim, Eu Suk" uniqKey="Kim E" first="Eu Suk" last="Kim">Eu Suk Kim</name>
<name sortKey="Kim, Hong Bin" sort="Kim, Hong Bin" uniqKey="Kim H" first="Hong Bin" last="Kim">Hong Bin Kim</name>
<name sortKey="Kim, Nam Joong" sort="Kim, Nam Joong" uniqKey="Kim N" first="Nam Joong" last="Kim">Nam Joong Kim</name>
<name sortKey="Lau, Eric H Y" sort="Lau, Eric H Y" uniqKey="Lau E" first="Eric H. Y." last="Lau">Eric H. Y. Lau</name>
<name sortKey="Man Poon, Leo Lit" sort="Man Poon, Leo Lit" uniqKey="Man Poon L" first="Leo Lit" last="Man Poon">Leo Lit Man Poon</name>
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<name sortKey="Perera, Ranawaka A P M" sort="Perera, Ranawaka A P M" uniqKey="Perera R" first="Ranawaka A. P. M." last="Perera">Ranawaka A. P. M. Perera</name>
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